Imaging single glycan molecules

Our paper in Nature

In our recent paper in Nature we were able to show direct imaging of single glycan molecules that are isolated by mass-selective, soft-landing electro spray ion beam deposition and imaged by low-temperature tunnelling microscopy. The sub-nanometre resolution of the technique enables the visualisation of glycan connectivity and discrimination between regioisomers. Direct glycan imaging is an important  step toward a better understanding of the structure of carbohydrates. 

 

The publication was featured in Nature Methods

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